ISS Vanguard is a 1-4 player co-operative, campaign board game. It will bring players right into an epic sci-fi adventure, as they play as 4 sections (security, re-con, science, engineering) onboard the first human ship to aim to reach outer space. Campaigns introduce a unique story written by Krzysztof Piskorski (Tainted Grail) full of hard player choices, twists and branching storylines. The game comes with over 100 different crew members, each with unique characteristics.

Gameplay is divided into 2 main stages: Ship phase and landing on planets.

During the Ship phase, players will manage their ship (binder with printed sleeves), where every section will have to make gameplay decisions. Then, you will prepare your crew for landing on the next planet, in search of answers to humanity's biggest questions. Together you will pick lander and customize it with modules, then each section will choose a crew member to take on a mission (more-experienced crew members have better ranks), build a skills deck, take equipment, and choose dice for your character.